CHEN LABORATORY 
Bacterial adaptation and Antibody function

RESEARCH

Our Research Interest

Now my independent lab broadly focuses on the following three areas: 1) determining the regulatory mechanisms of antibody function; 2) Developing protective antibodies and vaccines for certain pathogens; 3) bacteria-drugs interaction.


1. Developing antibody therapies and vaccines through understanding how antibody glycosylation, production, half-life, isotype-switching, and activity are regulated during immunizations or infections (bacteria and viruses).

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2. Developing the antibody-based interventions that not only provide antibody-mediated protection but also sensitize bacteria to antibiotics.

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3. Understanding the mechanisms of antibiotic resistance.

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